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Q&A with Dr. Chandra Bhattacharya: Designing a Novel Platform to Improve CAR T Cell Therapy

October 9, 2024

Chandrabali Bhattacharya, PhD, of the University of Nevada, Las Vegas, is developing a platform for in vivo CAR T cell therapy, which could have a tremendous impact on the field of cancer immunotherapy.

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Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy that has shown great success against treatment-resistant acute lymphoblastic leukemia, a type of aggressive blood cancer common in children.

However, CAR T cell therapy is a complex and very expensive process. It involves extracting the patient’s T cells, modifying them in a lab so they can detect and kill the cancer, and then reinjecting them into the patient.

Chandrabali Bhattacharya, PhD, an assistant professor at the University of Nevada, Las Vegas, received a 2024 PhRMA Foundation Faculty Starter Grant in Drug Delivery for her work to develop a platform for in vivo CAR T cell therapy, in which the modification of the T cells happens inside the body. If successful, this technology could have a tremendous impact on the field of immunotherapy by making CAR T cell therapy more efficient and more accessible to patients.

Watch this video to learn about Bhattacharya and her research.

 

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